Tmux & {Ctrl-Shift-C} and {Ctrl-Shift-V} bindings

How can I get the Linux system-wide copy/paste key combinations to work in tmux? I want to use them without a prefix key. I’d also need to be able to highlight text, but right now tmux just ignores that by removing the selection as soon as I finish.

I learned that this all works with the Shift key; i.e., Shift-MouseHighlight properly selects text and - still holding down the shift key – you can right-click and get the standard bash context menu with Copy, Paste, etc.

Ctrl-Shift-V does work to paste text in one of the panes, so that part’s OK